{"id":2675,"date":"2011-06-21T10:35:51","date_gmt":"2011-06-21T03:35:51","guid":{"rendered":"https:\/\/nano2.toolsmkt.com\/?p=2675"},"modified":"2011-06-21T10:35:51","modified_gmt":"2011-06-21T03:35:51","slug":"working-in-harmony","status":"publish","type":"post","link":"https:\/\/www.nanotec.or.th\/en\/working-in-harmony\/","title":{"rendered":"Working in Harmony"},"content":{"rendered":"<p>Researchers at the Massachusetts Institute of Technology (MIT), United States, have designed a new type of delivery system that allows nanoparticles to target tumors more effectively.\u00a0 <!--more-->Nanoparticles that deliver cancer drugs directly to tumors typically only get about one percent of the drug to the intended target.\u00a0 The new strategy, developed by MIT researchers, and colleagues from the Sanford-Burnham Medical Research Institute and the University of California at San Diego, also in the U.S., sends a first wave of nanoparticles to home in on the tumor, then calls in a much larger second wave, via a chemical reaction, that dispenses the cancer drug.\u00a0 The new strategy could enhance the effectiveness of many drugs for cancer and other diseases.\u00a0 According to Geoffrey von Maltzahn, a former MIT doctoral student now at Flagship VentureLabs, \u201cWhat we\u2019ve demonstrated is that nanoparticles can be engineered to do things like communicate with each other in the body, and that these capabilities can improve the efficiency with which they find and treat diseases like cancer.\u201d\u00a0 Studies in mice showed that one system of communication nanoparticles delivered 40 times more doxorubicin than non-communicating nanoparticles.\u00a0 Their findings were published in the online edition of the journal Nature Materials.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers at the Massachusetts Institute of Technology (MIT), United States, have designed a new type of delivery system that allows 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