{"id":10050,"date":"2016-06-14T08:54:30","date_gmt":"2016-06-14T01:54:30","guid":{"rendered":"http:\/\/www.nanotec.or.th\/en\/?p=10050"},"modified":"2016-06-14T08:54:30","modified_gmt":"2016-06-14T01:54:30","slug":"sirna-nanoparticles-reduce-post-heart-attack-inflammation","status":"publish","type":"post","link":"https:\/\/www.nanotec.or.th\/th\/sirna-nanoparticles-reduce-post-heart-attack-inflammation\/","title":{"rendered":"siRNA nanoparticles reduce post-heart attack inflammation"},"content":{"rendered":"<p class=\"standfirst\">Nanoparticles containing silencing RNA (siRNA) molecules could help reduce vascular inflammation after a heart attack and so lessen the risk of dangerous complications that might result. This is the new finding from researchers at the Massachusetts General Hospital (MGH) in Boston and the German Heart Center Munich, who have succeeded in supressing inflammation within atherosclerotic plaques in mice thanks to their technique. The work could help in the development of novel nanoparticle-based therapies for cardiovascular disease&#8230;&#8230;<\/p>\n<p>http:\/\/nanotechweb.org\/cws\/article\/tech\/65293<\/p>\n<div class=\"articleBody\">\n<div class=\"articleThumbnailLeft\"><a class=\"thickbox\" style=\"padding: 0px; margin: 0px; color: #0099cc; text-decoration: none;\" title=\"Aortic root protease activity significantly decreases in mice treated with siCAM5 (cell adhesion molecule), as shown by fluorescence molecular tomography (FMT)\/computed tomography (CT). Courtesy: H. Sager &lt;i&gt;et al.&lt;\/i&gt;, &lt;i&gt;Science Translational Medicine&lt;\/i&gt; (2016)]\" href=\"http:\/\/images.iop.org\/objects\/ntw\/news\/15\/6\/11\/pic1.jpg\"><img decoding=\"async\" title=\"Reducing inflammation\" src=\"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/11\/pic1.jpg\" alt=\"Reducing inflammation\" \/><\/a><br \/>\n<a class=\"thickbox\" style=\"padding: 0px; margin: 0px; color: #0099cc; text-decoration: none;\" title=\"Aortic root protease activity significantly decreases in mice treated with siCAM5 (cell adhesion molecule), as shown by fluorescence molecular tomography (FMT)\/computed tomography (CT). Courtesy: H. Sager &lt;i&gt;et al.&lt;\/i&gt;, &lt;i&gt;Science Translational Medicine&lt;\/i&gt; (2016)]\" href=\"http:\/\/images.iop.org\/objects\/ntw\/news\/15\/6\/11\/pic1.jpg\">Reducing inflammation<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Nanoparticles containing silencing RNA (siRNA) molecules could help reduce vascular inflammation after a heart attack and so lessen the risk [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[34,8],"tags":[],"class_list":["post-10050","post","type-post","status-publish","format-standard","hentry","category-technology-transfer","category-uncategorized-th"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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