{"id":10103,"date":"2016-06-24T08:54:12","date_gmt":"2016-06-24T01:54:12","guid":{"rendered":"http:\/\/www.nanotec.or.th\/en\/?p=10103"},"modified":"2016-06-24T08:54:12","modified_gmt":"2016-06-24T01:54:12","slug":"correlation-force-spectroscopy-reveals-tethering-effects-on-dna","status":"publish","type":"post","link":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/","title":{"rendered":"Correlation force spectroscopy reveals tethering effects on DNA"},"content":{"rendered":"<p class=\"standfirst\">The replication of DNA involves conformational changes are that are greatly affected by its mechanical properties. Tethering DNA has profound effects on its mechanical properties, but there are few studies that attempt to quantify this change. Researchers at Virginia Tech have developed and refined a technique that allows high-sensitivity force measurements of dynamic systems, and by applying it to single-stranded DNA they find that tethering affects the relaxation time by orders of magnitude&#8230;&#8230;&#8230;.<\/p>\n<p>http:\/\/nanotechweb.org\/cws\/article\/tech\/65222<\/p>\n<div class=\"articleBody\">\n<div class=\"articleThumbnailLeft\"><a class=\"thickbox\" style=\"padding: 0px; margin: 0px; color: #0099cc; text-decoration: none;\" title=\": a) Schematic of the experiment: a single polymer molecule (here two sections of ssDNA joined by a dsDNA section) straddles two AFM tips. &lt;i&gt;x&lt;\/i&gt;&lt;sub&gt;1&lt;\/sub&gt;(&lt;i&gt;t&lt;\/i&gt;)  and &lt;i&gt;x&lt;\/i&gt;&lt;sub&gt;2&lt;\/sub&gt;(&lt;i&gt;t&lt;\/i&gt;)  are the displacements of the thermally fluctuating tips, s is the tip-to-tip separation, &lt;i&gt;p&lt;\/i&gt; denotes z-piezo displacement and c is a constant. b) Each cantilever is modelled as a simple harmonic oscillator with mass mc, stiffness &lt;i&gt;k&lt;\/i&gt;&lt;sub&gt;c&lt;\/sub&gt;, and friction &lt;i&gt;&amp;xi;&lt;\/i&gt;&lt;sub&gt;11&lt;\/sub&gt;. &lt;i&gt;&amp;xi;&lt;\/i&gt;&lt;sub&gt;12&lt;\/sub&gt; is the friction due to the fluid coupling. &lt;i&gt;k&lt;\/i&gt;&lt;sub&gt;ssDNA&lt;\/sub&gt; and &lt;i&gt;&amp;xi;&lt;\/i&gt;&lt;sub&gt;ssDNA&lt;\/sub&gt; are the stiffness and friction of ssDNA that straddles between the tips. In the symmetric mode the cantilevers move in the same direction, while in the asymmetric mode they move in opposite directions. Courtesy &lt;a href=&quot;http:\/\/iopscience.iop.org\/article\/10.1088\/0957-4484\/27\/25\/255701&quot; target=&quot;_blank&quot;&gt;&lt;i&gt;Nanotechnology&lt;\/i&gt;&lt;\/a&gt;\" href=\"http:\/\/images.iop.org\/objects\/ntw\/news\/15\/6\/8\/image.jpg\"><img decoding=\"async\" title=\"Schematic of the experiment\" src=\"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/8\/image.jpg\" alt=\"Schematic of the experiment\" \/><\/a><br \/>\n<a class=\"thickbox\" style=\"padding: 0px; margin: 0px; color: #0099cc; text-decoration: none;\" title=\": a) Schematic of the experiment: a single polymer molecule (here two sections of ssDNA joined by a dsDNA section) straddles two AFM tips. &lt;i&gt;x&lt;\/i&gt;&lt;sub&gt;1&lt;\/sub&gt;(&lt;i&gt;t&lt;\/i&gt;)  and &lt;i&gt;x&lt;\/i&gt;&lt;sub&gt;2&lt;\/sub&gt;(&lt;i&gt;t&lt;\/i&gt;)  are the displacements of the thermally fluctuating tips, s is the tip-to-tip separation, &lt;i&gt;p&lt;\/i&gt; denotes z-piezo displacement and c is a constant. b) Each cantilever is modelled as a simple harmonic oscillator with mass mc, stiffness &lt;i&gt;k&lt;\/i&gt;&lt;sub&gt;c&lt;\/sub&gt;, and friction &lt;i&gt;&amp;xi;&lt;\/i&gt;&lt;sub&gt;11&lt;\/sub&gt;. &lt;i&gt;&amp;xi;&lt;\/i&gt;&lt;sub&gt;12&lt;\/sub&gt; is the friction due to the fluid coupling. &lt;i&gt;k&lt;\/i&gt;&lt;sub&gt;ssDNA&lt;\/sub&gt; and &lt;i&gt;&amp;xi;&lt;\/i&gt;&lt;sub&gt;ssDNA&lt;\/sub&gt; are the stiffness and friction of ssDNA that straddles between the tips. In the symmetric mode the cantilevers move in the same direction, while in the asymmetric mode they move in opposite directions. Courtesy &lt;a href=&quot;http:\/\/iopscience.iop.org\/article\/10.1088\/0957-4484\/27\/25\/255701&quot; target=&quot;_blank&quot;&gt;&lt;i&gt;Nanotechnology&lt;\/i&gt;&lt;\/a&gt;\" href=\"http:\/\/images.iop.org\/objects\/ntw\/news\/15\/6\/8\/image.jpg\">Schematic of the experiment<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>The replication of DNA involves conformational changes are that are greatly affected by its mechanical properties. Tethering DNA has profound [&hellip;]<\/p>\n","protected":false},"author":27,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[34,8],"tags":[],"class_list":["post-10103","post","type-post","status-publish","format-standard","hentry","category-technology-transfer","category-uncategorized-th"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Correlation force spectroscopy reveals tethering effects on DNA - \u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Correlation force spectroscopy reveals tethering effects on DNA - \u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34\" \/>\n<meta property=\"og:description\" content=\"The replication of DNA involves conformational changes are that are greatly affected by its mechanical properties. Tethering DNA has profound [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/\" \/>\n<meta property=\"og:site_name\" content=\"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34\" \/>\n<meta property=\"article:published_time\" content=\"2016-06-24T01:54:12+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/8\/image.jpg\" \/>\n<meta name=\"author\" content=\"dtmd-saw\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"dtmd-saw\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/\"},\"author\":{\"name\":\"dtmd-saw\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#\\\/schema\\\/person\\\/88218bb3e9b90374bb344b36afd79a87\"},\"headline\":\"Correlation force spectroscopy reveals tethering effects on DNA\",\"datePublished\":\"2016-06-24T01:54:12+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/\"},\"wordCount\":91,\"publisher\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/images.iop.org\\\/objects\\\/ntw\\\/news\\\/thumb\\\/15\\\/6\\\/8\\\/image.jpg\",\"articleSection\":[\"Technology Transfer\",\"Uncategorized @th\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/\",\"url\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/\",\"name\":\"Correlation force spectroscopy reveals tethering effects on DNA - \u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/#primaryimage\"},\"thumbnailUrl\":\"http:\\\/\\\/images.iop.org\\\/objects\\\/ntw\\\/news\\\/thumb\\\/15\\\/6\\\/8\\\/image.jpg\",\"datePublished\":\"2016-06-24T01:54:12+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/#primaryimage\",\"url\":\"http:\\\/\\\/images.iop.org\\\/objects\\\/ntw\\\/news\\\/thumb\\\/15\\\/6\\\/8\\\/image.jpg\",\"contentUrl\":\"http:\\\/\\\/images.iop.org\\\/objects\\\/ntw\\\/news\\\/thumb\\\/15\\\/6\\\/8\\\/image.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Correlation force spectroscopy reveals tethering effects on DNA\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#website\",\"url\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/\",\"name\":\"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34\",\"description\":\"(NANOTEC)\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#organization\",\"name\":\"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34\",\"url\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/wp-content\\\/uploads\\\/2025\\\/08\\\/Nanotec-2-logo.png\",\"contentUrl\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/wp-content\\\/uploads\\\/2025\\\/08\\\/Nanotec-2-logo.png\",\"width\":1332,\"height\":391,\"caption\":\"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34\"},\"image\":{\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/#\\\/schema\\\/person\\\/88218bb3e9b90374bb344b36afd79a87\",\"name\":\"dtmd-saw\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ae435d88d45984c48e97b21812199caa72ce225985ce4fd01f09f8c6db4785ea?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ae435d88d45984c48e97b21812199caa72ce225985ce4fd01f09f8c6db4785ea?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/ae435d88d45984c48e97b21812199caa72ce225985ce4fd01f09f8c6db4785ea?s=96&d=mm&r=g\",\"caption\":\"dtmd-saw\"},\"url\":\"https:\\\/\\\/www.nanotec.or.th\\\/th\\\/author\\\/dtmd-saw\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Correlation force spectroscopy reveals tethering effects on DNA - \u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/","og_locale":"en_US","og_type":"article","og_title":"Correlation force spectroscopy reveals tethering effects on DNA - \u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34","og_description":"The replication of DNA involves conformational changes are that are greatly affected by its mechanical properties. Tethering DNA has profound [&hellip;]","og_url":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/","og_site_name":"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34","article_published_time":"2016-06-24T01:54:12+00:00","og_image":[{"url":"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/8\/image.jpg","type":"","width":"","height":""}],"author":"dtmd-saw","twitter_card":"summary_large_image","twitter_misc":{"Written by":"dtmd-saw"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/#article","isPartOf":{"@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/"},"author":{"name":"dtmd-saw","@id":"https:\/\/www.nanotec.or.th\/th\/#\/schema\/person\/88218bb3e9b90374bb344b36afd79a87"},"headline":"Correlation force spectroscopy reveals tethering effects on DNA","datePublished":"2016-06-24T01:54:12+00:00","mainEntityOfPage":{"@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/"},"wordCount":91,"publisher":{"@id":"https:\/\/www.nanotec.or.th\/th\/#organization"},"image":{"@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/#primaryimage"},"thumbnailUrl":"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/8\/image.jpg","articleSection":["Technology Transfer","Uncategorized @th"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/","url":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/","name":"Correlation force spectroscopy reveals tethering effects on DNA - \u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34","isPartOf":{"@id":"https:\/\/www.nanotec.or.th\/th\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/#primaryimage"},"image":{"@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/#primaryimage"},"thumbnailUrl":"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/8\/image.jpg","datePublished":"2016-06-24T01:54:12+00:00","breadcrumb":{"@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/#primaryimage","url":"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/8\/image.jpg","contentUrl":"http:\/\/images.iop.org\/objects\/ntw\/news\/thumb\/15\/6\/8\/image.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.nanotec.or.th\/th\/correlation-force-spectroscopy-reveals-tethering-effects-on-dna\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.nanotec.or.th\/th\/"},{"@type":"ListItem","position":2,"name":"Correlation force spectroscopy reveals tethering effects on DNA"}]},{"@type":"WebSite","@id":"https:\/\/www.nanotec.or.th\/th\/#website","url":"https:\/\/www.nanotec.or.th\/th\/","name":"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34","description":"(NANOTEC)","publisher":{"@id":"https:\/\/www.nanotec.or.th\/th\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.nanotec.or.th\/th\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.nanotec.or.th\/th\/#organization","name":"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34","url":"https:\/\/www.nanotec.or.th\/th\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.nanotec.or.th\/th\/#\/schema\/logo\/image\/","url":"https:\/\/www.nanotec.or.th\/th\/wp-content\/uploads\/2025\/08\/Nanotec-2-logo.png","contentUrl":"https:\/\/www.nanotec.or.th\/th\/wp-content\/uploads\/2025\/08\/Nanotec-2-logo.png","width":1332,"height":391,"caption":"\u0e28\u0e39\u0e19\u0e22\u0e4c\u0e19\u0e32\u0e42\u0e19\u0e40\u0e17\u0e04\u0e42\u0e19\u0e42\u0e25\u0e22\u0e35\u0e41\u0e2b\u0e48\u0e07\u0e0a\u0e32\u0e15\u0e34"},"image":{"@id":"https:\/\/www.nanotec.or.th\/th\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/www.nanotec.or.th\/th\/#\/schema\/person\/88218bb3e9b90374bb344b36afd79a87","name":"dtmd-saw","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/ae435d88d45984c48e97b21812199caa72ce225985ce4fd01f09f8c6db4785ea?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/ae435d88d45984c48e97b21812199caa72ce225985ce4fd01f09f8c6db4785ea?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/ae435d88d45984c48e97b21812199caa72ce225985ce4fd01f09f8c6db4785ea?s=96&d=mm&r=g","caption":"dtmd-saw"},"url":"https:\/\/www.nanotec.or.th\/th\/author\/dtmd-saw\/"}]}},"_links":{"self":[{"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/posts\/10103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/users\/27"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/comments?post=10103"}],"version-history":[{"count":0,"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/posts\/10103\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/media?parent=10103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/categories?post=10103"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nanotec.or.th\/th\/wp-json\/wp\/v2\/tags?post=10103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}