Workshop on “The Development of Nanostructure Lipid Carrier from Sugarcane Wax for enhancing characteristics of lipstick and nail polishers”

A workshop on “The Development of Nanostructure Lipid Carrier from Sugarcane Wax for lipstick and nail polisher” was jointly hosted by NSTDA, NRCT, TRF, and NANOTEC at Sofitel Hotel in Bangkok, Thailand. The aim of the workshop is to build awareness of the cosmetic industry to the utilization of nanotechnology to produce novel products from sugar waste such as lipstick and nail polishers which have cool soothing and moisturizer effect. Thailand is the 2nd largest sugar exporter behind Brazil according to Statista. In 2013, Thailand export of sugar was 7 million metric tons. Each year large amounts of press mud are released by the sugarcane industry and the disposal of this by-product is a major issue. In many cases press mud is burnt in brick kilns resulting in the loss and wastage of millions of tonnes of nutrients through burning, which ultimately degrades the environment. One common use is as fertilizer, in unprocessed or processed form. Another option is to separate the sugarcane wax from the press mud.  With the global trend of health maintenance and nutrition products on the increase, the market for nutraceutical products are also on the rise and Thailand is one of the key markets as both producer and importer. Thai researchers are looking at ways to use nanotechnology to add value to the sugarcane wax and change it into a high-value nano-material for cosmetic industry and functional ingredients to nutraceutical products.  In 2013, three NANOTEC researchers (Dr. Ubonthip Nimmannit, Dr. Kittiwut Kasemwong, and Dr. Apirada Sucontphunt) received a research fund from Thailand Research Fund (TRF) and National Research Council Thailand (NRCT) via the Strategic Basic Research Programme  to explore the economics of sugarcane wax. The project was concluded in July 2013.  The research program compose of 2 research projects; 1. An Economic Analysis of Worthiness on Sugarcane Wax Production as Carriers for Delivery System of Bioactive Compounds (Dr. Kittiwut conducted the project as Project Investigator). 2. Product Development of Nanostructure Lipid Carrier from Sugarcane Wax for Application in Sunscreen and Moisture Nail Lotion (Dr. Apirada led this project).  “The aim of the research project was to use nanotechnology to add value to the Press Mud and change to the high-value nano-material for cosmetic industry and functional ingredients to nutraceutical products” said Dr. Ubonthip, Senior Researcher/Team Leader (Nano-cosmeceutical Lab) and Director of NANOTEC Development Unit.  Collaborators on the research included Kasetsart University, Thammasat University, Srinakharinwirot University and PTT Global Chemical Public Company.  IMG_00361 IMG_00351

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Governor visit field testing of Nano Smart Soil Mobile Unit

NANOTEC Nano Smart Soil Mobile Unit has been stationed at the Chulalongkorn Watergate in Pathumthani province since Oct 1 as part of its field testing activity. The governor of Pathumthani Khun Pongsatorn Sajjacholapund, Khun Teerawoot Klinkusoom, Mayor of Rangsit City Municipality, and senior officials paid a visit to observe the field testing. Both the governor and mayor used this opportunity to explore ways in which collaboration can be solidified in order that economic and social impact can be generated from the research. The mobile unit is expected to complete the field testing activity in the middle of October. [caption id="attachment_7669" align="alignnone" width="640"]IMG_9899 (Small) The governor visit the mobile unit[/caption] IMG_9929 (Small) IMG_9962 (Small)

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Zeta technology received Merit Award at National Innovation Day 2014

On June 20, 2006 the government endorsed the proposal by the Ministry of S&T to honor HM the King as Father of Thai Innovation for his achievement in the royal initiative project “Tricking the soil”. To commemorate this auspicious occasion, the National Innovation Day is held on Oct 5 of every year.  Congratulations to Dr. Kittiwut Kasemwong, researchers at NANOTEC Nano Delivery System Lab, and Dr. Kitti Supchukun MD of KLEAN Greentech Co.,Ltd whose joint research on “Zeta-Technology” a mycotoxin binding for animal feed (pork, poultry, and fish) received the Merit Award at the National Innovation Day 2014 on October 5 at Centara Grand Hotel in Bangkok. Dr. Sumet Tanti-Vejkul opened the award ceremony. The award categories are Economic Contribution and Social Contribution.  “The joint research did not actually take very long to accomplished, it only took 2 days to discussed and 4 months to produce the first commercial samples, this is due to the fact that Dr. Kittiwut and his research colleagues already have the knowledge on nano delivery system” said Dr. Kitti. “The zetatechnology is already commercialized under the name ZetaL-Tonic and we plan to list the product register it in MAI (Market for Alternative Investment) of the Stock Exchange of Thailand within 2 years. This listing will be a highlight of our accomplishment”.  Zetatechnology employs nanotechnology in selecting various types of nanoclay particles and transform their structure into nanocomposite. The processes helps promote reinforce action, enabling the products to effectively absorb all types of mucotoxin that pose problems in livestock production.  The economic and social benefits of mycotoxin binder which is used for absorbing contaminants in animal feed ingredient can help minimize farmers’ losses in the livestock production. Thailand’s annual import of mycotoxin binder products stand at around Baht 1.4 billion and this innovation will greatly help to reduce import. IMG_9732 (Small) IMG_9787 (Small)

Technology Update

Nanoparticle-induced autophagy could help improve cancer treatments

Rare-earth oxide (REO) nanoparticles interfere with a mechanism called autophagic flux in biological cells by inhibiting several important cellular processes but quartz nanoparticles and multiwalled carbon nanotubes (MWCNTs) appear to have no adverse effects on autophagy (a process in which cells seem to "self-digest" in the presence of stressors). This new finding, from researchers at the University of California at Los Angeles and the California NanoSystems Institute, could be important for preventing inflammatory diseases such as lung fibrosis and treating cancer in its early stages. Artificially enhancing autophagy using REOs might even be used to help in the treatment of neurodegenerative diseases by removing unwanted aggregated proteins and mitochondria and so allow more neurons to survive......


Multilayer graphene is a clear candidate for displays

Electrochromic devices, which allow the transmittance of light to be adjusted by applying a voltage, sound like a strong competitor to liquid crystal displays. Yet despite their proposed advantages of low cost and mechanical flexibility, fragile materials and material mismatches with the electrodes have so far hindered the performance of these newcomers in display technology. Now an all-graphene electrochromic device has demonstrated 55% modulation, as well as a broad spectral response, making it a clear candidate for smart windows and displays.....


Graphene aerogels go crystalline

A new way to make graphene oxide-based aerogels containing highly crystalline graphene sheets has been developed by researchers in California. The aerogels – which might find use in catalysts, energy-storage devices, sensors, composites and even in desalination technologies – are much better than previously made foams that were of a much poorer quality......


Plasma engineers BN surface

Nanostructured boron nitride (BN) is a technologically important material thanks to its excellent mechanical and thermal properties. It could be ideal for use in a variety of electronics and optoelectronics applications and as a good support material for graphene devices because the two materials have very similar lattice constants. However, BN is notoriously difficult to functionalize because it is chemically inert and hydrophobic. A new and simple one-step plasma-assisted technique to add hydroxyl groups to the material, developed by researchers at the National Institute for Materials Science (NIMS) in Tsukuba, Japan, may now help overcome this problem....

Nano Talk

Special Talk: Nanoporous Catalysts for Cleaner Energy and Environment

Invitation to attend: Special Talk on "Nanoporous Catalysts  for Cleaner Energy and Environment" Speaker: Asst. Prof. Watcharop Chaikittisilp, Department of Chemical System Engineering, University of Tokyo Date: October 29 Time: 10:00 - 11:15 AM Venue: Innovation Zone (INC 2) Free registration to: (Presentation in Thai) IMG_3340_-copy1-230x300


NANO Talk: From conceptualization to product shelf-life: A story on innovation of Strateris "second skin" platform.

Invitation to attend: NANO Talk:  From conceptualization to product shelf-life: A story on innovation of Strateris "second skin" platform. Speaker:         Ariya Akthakul, Ph.D. - Principal Engineer, Skincare & New Material Discovery, LivingProof Inc, Cambridge, MA 02142 (USA) Date:                  Tuesday Nov 11 (10:00 - 11:30) Venue:             NANOTEC Innovation Zone, NANOTEC, INC 2 Bldg. B (Thailand Science Park) Free registration to: Presentation in Thai Abstract: This talk is a case study of a commercial platform called Strateris - on how a novel material has emerged from initial conceptualization, to system design and feasibility, then to packaging and commercialization. The plan for Strateris is to create an imperceptible, breathable, elastic "second skin"; that delivers additional skin properties beyond the skin itself. Potential examples include controlled drug delivery (SPFs, vitamins, APIs), wound healing, optical modification on skin (wrinkles & under-eye bags), as well as skin mechanical rejuvenation and support. I will demonstrate a specific example of Strateris platform for under-eye bag and wrinkle reduction. Here, I divided the timelines into 4 stages of design aspects: (i) Initial conceptualization of a novel material platform where the main task is to enlist expected performance criteria, and then to translate them into corresponding material properties. For Strateris, the concept is to come up with flexible materials of good elasticity, optically-scattered, good skin-adhesion, and surface resistance to environment (water in particular). Such performance criteria can be categorized into three buckets of material properties: mechanical, optical, and transport. (ii) Once target properties are identified, the focus of the work is then shifted to molecular design for an optimal material system. For Strateris, a tunable silicone-based composite elastomer by-design could satisfied the required performances. (iii) The next task is to deliver such material system onto the skin in a user-friendly and economical way - which includes recipe formulation & scale-up manufacture. For Strateris, we employed a two-step water-in-silicone emulsion system to deposit target composite elastomers via an in-situ crosslinking polymerization - with scale-up capability. At this stage, one major obstacle remains a high-throughput screening tool for optimizing formulation candidates where in-vivo to in-vitro performance correlations need to be established. (iv) Then, the system is ready to be packaged into a product where the next stage is to verify the shelf-life or product stability against any perturbations such as heat, humidity, gravity, and vibration from transport. Without a real-time product stability data, the main challenges lie in how to formulate a quantitative prediction of shelf-life based on "accelerated conditions", and how to identify critical attributes that truly represent the product stability. I will demonstrate how a lesson learned from Strateris can be adapted for future product developments. About Dr. Ariya Ariya Akthakul, Ph.D. Principal Engineer, Skincare & New Material Discovery, LivingProof Inc, Cambridge, MA 02142 (USA) Ariya earned his Ph.D. in Materials Science and Engineering from MIT, working in Anne Mayes’s Lab designing a molecular platform for surface self-organization of their patented copolymers. His demonstrations on how these copolymers improved the water filtration membranes for their productivity & bio-fouling resistance have earned him several scientific publications, patents, and awards from MIT, American Physical Society, and Materials Research Society. Prior to joining LivingProof, Ariya has led a sensor development team for an electronic nose device at CogniScent, Inc., where he served as its R&D Sensor Development Manager for five years. At CogniScent, he played a vital role in securing SBIR grants to R&D program, as well as external collaborations such as UMass Lowell and Law Enforcement Agencies. Prior to CogniScent, Ariya has been a critical team member of Process Analytical Technology (PAT) initiation at Bristol-Myers Squibb, where he brought in a real-time quality assurance and process understandings throughout each pharmaceutical unit process. Currently at LivingProof, Ariya is actively involved in new material discovery for Strateris™ platform - which is a highly elastic, flexible, breathable, non ‐ irritating, non ‐ toxic, and invisible micron ‐ thick polymer film with tunable properties for a wide range of medical, surgical, and aesthetic applications. ariya-akthakul-ph-d  


Risk Management of R&D and Gate Stage process

Risk management is anything one does to reduce exposure to liability. In research and development risk management is taken very seriously. Obviously, it is not possible to completely implement all the necessary steps pertaining to risk management of a research institution due to various constraints such as budget, manpower, uncertainty in policy/information, environment, and process. On August 25, NANOTEC invited Mr. Khemadhat Sukondhasingha, a member of NANOTEC Executive Board who is considered an expert in the topic to give a talk on “Risk Management of R&D & Stage Gate Model” to researchers, policy staff, and senior management. "NSTDA is in the business of research development. Therefore, it is important that research agencies within NSTDA clearly understands the significant benefits of risk management from a business sense" said Mr. Khemadhat. "By being able to use risk management process such as Technology Readiness Level (TRL) and Stage Gate Model will help to better organize research directions to create impact success". Mr.Khemadhat also mentioned the importance of Business Development Unit also known as Technology Management Unit to be a vital part of risk management. "Business Development is NOT the same as Marketing. Business Development  must be in the position to provide information regarding consumers' needs and help put together specific technology package that can be presented to potential customers. Doing so will help research projects move up the TRL chart". NANO Talk is a monthly public forum organized by NANOTEC for researchers and visiting professors to exchange knowledge and be updated on technology trends. Visiting professors to Thailand are encouraged to participate. IMG_85251    


NANO Talk: "Risk Management of R&D & Stage Gate Model".

Invitation to attend: NANO Talk on ""Risk Management of R&D & Stage Gate Model" Speaker: Mr. Khemadhat Sukondhasingha, member of NANOTEC Executive Board Date: Monday, August 25 Time: 14:00 - 15:30 Venue:  INC 2 Board Room (4th floor) Free registration and presentation in Thai Khemathat1


Seminar on “The Development of Nanostructure Lipid Carrier from Sugarcane Wax for Cosmetic Applications” (Sept 29-30)

A seminar on “The Development of Nanostructure Lipid Carrier from Sugarcane Wax for Cosmetic Applications” was jointly hosted by NSTDA, NRCT, TRF, and NANOTEC at Dusit Thani Hotel in Pattaya, Thailand. [gallery ids="7642,7643,7644,7645,7646,7647,7648,7649,7650,7651,7652,7653,7654"]  


Send-off celebration for Nano Smart Soil Mobile Unit (Oct 1)

NANOTEC in collaboration with Pathumthani municipality will mobilize the Nano Smart Soil mobile unit to help with getting rid of water hyacinth at Chulalongkorn Watergate [gallery ids="7622,7621,7620,7619,7618,7617,7616,7615,7612"]  


Thai Army Innovation Day 2014 (Sept 11)

NSTDA research agencies consisting of NECTEC (Smart Tracking, T-Box, SER, and SWOT), MTEC (Armour Plate) and NANOTEC joined the Royal Thai Army Invention Day 2014 at the Thai Army Sport Club on September 11. NANOTEC display research related to 3 Flagship programs: Mosquito Control, Future Energy, and Smart Soil . The event was opened by Gen. Aksra Kerdphol , Chief of Staff.   [gallery ids="7526,7525,7518"]  


NRCT launch Invention Contest 2015

Prof. Soottiporn Chittmittrapap, Secretary-General of National Research Council of Thailand (NRCT) official opened the NRCT Invention Contest 2015 on September 9, 2014 [gallery ids="7493,7494,7495,7496,7497,7498"]  

Nano Safety
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OECD countries address the safety of manufactured nanomaterials

The OECD has recommended its Member Countries apply existing international and national chemical regulatory frameworks to manage the risks associated with manufactured nanomaterials...... logooecd_en (Small)

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Workshop on Implementation of Nanosafety and Ethics Strategic Plan: Action Plan to AEC

In a recent Asian-Pacific Newsletter on Occupational Health and Safety (Vol 19, number 3, December 2012), Prof. Sirirurg Songsivilai, NANOTEC Executive Director emphasized that the number of products currently on the market containing nanomaterials as the critical component or uses nanotechnology in crucial manufacturing process will increase from 1% to 10% in the coming decade. This is a significant increase and one which needs public attention as this may have impact on everyday life. In his recent speech to the participants of the workshop on “The Implementation of Nanosafety and Ethics Strategic Plan: Action Plan to AEC”, Prof. Sirirurg informed that the Thai government approved in 2012 the National Nanosafety and Ethics Policy Framework as the critical check and balance to the National Nanotechnology Policy Initiative to ensure sustainable development of nanotechnology. “The workshop will help to strengthen the understanding of the safety aspects of nanotechnology for representatives from associated organizations; government, public, and private sector, and will allow for establishment of the action plan for the Nanosafety and Ethics Strategic Plan 2012-2016” said Prof. Sirirurg. “In order to implement the action plan of Nanosafety and Ethics Strategic Plan, effectively and comprehensively, we must focus not only on the planning process, but the monitoring and evaluation process”. The workshop which was held on April 2 at Thailand Science Park was funded by the United Nations Institute for Training and Research (UNITAR) and Swiss Confederation, and organized by NANOTEC and NSTDA. The workshop was held in conjunction with the NSTDA Annual Conference 2013 (NAC 2013). Speaking on behalf of Swiss Confederation, Mrs. Daniela Schneider extended her gratitude to the Thai government for their leadership in promoting public awareness to the emerging issue of nano technology and manufactured nano materials. “Thailand has set an important example in the Asian region by creating an agency to coordinate the management of nanotechnology at a national level” said Daniela. “We believe that Thailand has the potential to take a leading role in this exciting new area at the regional or sub-regional level and we are willing to support such sub-regional collaboration”. Also echoing Daniela’s comment is Mr. Georg Karlaganis, Training Advisor, Chemicals and Waste Management Program, United Nations Institute for Training and Research (UNITAR) who said that in the field of nano safety management Thailand is ahead compared to others. He went on to say that the public engagement activities in Thailand set a good introductory example for other countries to follow. This is not the first time that the 4 organization have join force to organize a public engagement activity. In 2012 a public seminar was held in Khon Kaen province during NanoThailand 2012 to address the topic of “Society, Nanosafety and Ethics on Nanotechnology Development”. The various nanosafety workshops that have been organized by the 4 organization in the past stemmed from the signed 2011 NANOTEC- UNITAR Memorandum of Agreement to implement a Training and Capacity Building for the Development of the Nano-Safety Pilot project in Thailand (phase 1). Based on the positive results of the phase 1 project and from the clear message of SAICM ICCM3 Nairobi meeting, UNITAR & Swiss Confederation have decided to continue support for a second phase of the nano pilot projects with NANOTEC. [gallery link="file" columns="2"]

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Seminar on Nano-Characterization and Testing service for AEC opens

With the increase in nano related products in the market and the establishment of the Asean Economic Community (AEC) in 2015, the question of safety becomes an even bigger concern for the consumer. In a recent Asian-Pacific Newsletter on Occupational Health and Safety (Vol 19, number 3, December 2012), Prof. Sirirurg Songsivilai, NANOTEC Executive Director emphasized that the number of products currently on the market containing nanomaterials as the critical component or uses nanotechnology in crucial manufacturing process will increase from 1% to 10% in the coming decade. This is a significant increase and one which needs public attention as this may have impact on everyday life. To give priority to this topic, NANOTEC joined the NSTDA Annual Conference 2013 (NAC 2013) to organize a seminar at Thailand Science Park under the theme “Nano-Characterization and Testing Service for AEC”. The seminar looks at nanoscale analytical testing, regulations of nanoproducts, testing techniques, metrological at nanoscale, and the approach to using NanoQ in Thailand. Over 150 participants from public, academia, and private sector attended the seminar.
“The AEC landscape is quite complex given the fact that there are more people, more competition, more movement of capital and technology, and more movement of human resources” said Dr. Chainarong Cherdchu, Senior Advisor at NANOTEC. “The importance of having conformity of standards and quality especially in measurement will be an important topic once AEC comes of age. Therefore, it is necessary that we all become aware and understands exactly what is involved”. NanoQ label also took front stage with a presentation by Mr. Por Punyaratabandhu, Chairman of NanoQ Label, Nanotechnology Association of Thailand. The talk entitled “The Practical Approach: NanoQ” provides information on the benefits of NanoQ label to 4 private sector groups: ceramic, plastic, textile, and paints. The first NanoQ label was presented in September 2012 to Supreme Products Co.,Ltd. The NanoQ label certified that the paint formulation produced by Supreme Product for use in coating the inside of the ambulance contains silver nano particles that have characteristics of anti bacteria. The testing of the paint formulation samples was performed by researchers at Nano Characteristic Lab at NANOTEC. This certification is good for 2 years. Since then, the association has received interest from various companies inquiring about the application for NanoQ label for their product. [gallery link="file" columns="2"]

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3rd Thailand-Korea Nanobiotechnology Joint Research Meeting opens

The 3rd Thailand – Korea Nanobiotechnology Joint Research Meeting opened this morning with Prof. Sirirurg Songsivilai, NANOTEC Executive Director presenting the Opening Remarks. According to Prof. Sirirurg the meeting provides a venue for interaction and mixing between nanobiotechnology researchers that will create the research sparks that the local research community needs. Prof. Sirirurg gestured a symbolic comparison of the gathering to that of the late Steve Jobs push for human interaction and creativity at his Pixar Animation Studio in the USA. Prof. Sirirurg told the story of the 2 bathrooms at Steve Jobs’ Pixar Animation studio. According to Prof. Sirirurg, Steve Jobs insisted there be only two bathrooms in the entire Pixar studios, and that these would be in the central space. And of course this is very inconvenient. No one wants to have to walk 15 minutes to go to the bathroom. And yet he insisted that this is the one place everyone has to go every day. If you do happen to visit Pixar, ask them about their 'bathroom story.' They all talk about the great conversation they had while washing their hands. He went on to say that Steve Jobs wanted there to be mixing. He knew that the human friction makes the sparks, and that when you're talking about a creative endeavor that requires people from different cultures to come together, you have to force them to mix; that our natural tendency is to stay isolated, to talk to people who are just like us, who speak our private languages, who understand our problems. But that's a big mistake. And so his design was to force people to come together even if it was just going to be in the bathroom. Leading the Korean team was Dr. Bong Hyun Chung, Director of BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB). “The field of convergence is one of the key engines for economic growth and creation of jobs under the new government” said Prof. Chung. “When there is successful commercialization of new technology, this helps to contribute to the economy of any nation”. Prof. Chung went on to inform that the new Korean government has assigned science and technology portfolio to be under the Ministry of Future, Creation and Science (MFCS). The new ministry will be involved in promoting investment in research and development. The 3 days meeting from March 29-31 in Bangkok is organized by NANOTEC and KRIBB to promote research collaboration opportunities between Thailand and Korea. A total of 25 experts took turn to present technical papers and exchange dialogue on selected research projects. In addition, the program also included the Networking and Discussion session on 4 themes: Nanomedicine, NanoSafety, and NanoBiosensor. The 4th meeting in 2014 will take place in Korea hosted by KRIBB. [gallery link="file" columns="2"]

Thailand Science Park

Thailand Science Park

Thailand's investment in infrastructure to support R&D: The Thailand Science Park

Thailand participate at 3rd ICCM

Thailand participate at 3rd ICCM

Dr. Sirirurg Songsivilai, Director of NANOTEC (Thailand's Nanotechnology Center) spoke at the plenary session of SAICM (Strategic Approach to International Chemical Management) about nanosafety and nano ethics in Thailand at the 3rd ICCM (International Conference on Chemical Management) on 18 September 2012 in Nairobi, Kenya.

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BBC Click (edited version)

 Using nanotechnology for natural disaster mitigation in Thailand IMG_1400 (Medium) To watch this video, please press this link.