The cellular membrane represents the ultimate barrier for the delivery of therapeutic molecules into living cells. A variety of methods are available to cross it, but all have different disadvantages. A new technique utilizing the interaction of gold nanoparticles (AuNPs) with laser pulses, termed gold nanoparticle mediated (GNOME) laser transfection, adds versatility to the common techniques. It has been proven to efficiently deliver fluorescent molecules, siRNA, and Morpholino oligomers. Reporting here inNanotechnology, researchers present its applicability to the injection of functional proteins into living cells. The viability of the cells is conserved while simultaneously reaching high throughput………
http://nanotechweb.org/cws/article/lab/57342
