The self-assembly of macromolecules into organized, hierarchical structures is one of the most characteristic features of biological systems, but mimicking this process in the lab with artificial materials is no easy task. Now, a team of researchers at the University of Massachusetts at Amherst has succeeded in self-assembling such superstructures by simply mixing together proteins and nanoparticles. The added bonus is that the structures can also deliver the proteins to the cytosol of cells, where they can then be directly transported to the cell nucleus. Using this strategy for protein-based gene editing therapy is a new way to treat a wide range of genetic maladies, including chronic inflammation, cerebrovascular disorders and cancer…..
http://nanotechweb.org/cws/article/tech/67976
